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リグニンスルホン酸による食後高血糖抑制作用
http://hdl.handle.net/10258/00009179
http://hdl.handle.net/10258/00009179c711e33c-4e68-49bb-b50d-8ac2130a4ffd
名前 / ファイル | ライセンス | アクション |
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66_11.pdf (1.1 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
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公開日 | 2017-03-23 | |||||||||||
タイトル | ||||||||||||
言語 | ja | |||||||||||
タイトル | リグニンスルホン酸による食後高血糖抑制作用 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | Lignosulfonic acid suppresses postprandial hyperglycemia | |||||||||||
言語 | ||||||||||||
言語 | jpn | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | lignin | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | diabetes | |||||||||||
キーワード | ||||||||||||
言語 | ja | |||||||||||
主題Scheme | Other | |||||||||||
主題 | α-glucosidase | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | departmental bulletin paper | |||||||||||
アクセス権 | ||||||||||||
アクセス権 | open access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
著者 |
門田, 有起也
× 門田, 有起也× 中川, 絵利奈× 川南, 諭× 長谷川, 靖
WEKO
10436
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室蘭工業大学研究者データベースへのリンク | ||||||||||||
長谷川 靖(HASEGAWA Yasushi) | ||||||||||||
http://rdsoran.muroran-it.ac.jp/html/100000200_ja.html | ||||||||||||
抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Lignosulfonic acid is a waste lignin produced from the sulfite pulping of softwood. We investigated the effect of lignosulfonic acid on α-glucosidase and found that lignosulfonic acid produced a reversible and non-competitive inhibition of the enzyme activity. Moreover, in human colorectal adenocarcinoma cells, lignosulfonic acid inhibited 2-deoxyglucose uptake, while in vivo studies demonstrated a significant reduction in the blood glycemic response to sucrose or glucose ingestion in rats treated with lignosulfonic acid. Feces of rats fed a diet supplemented with 5% lignosulfonic acid had higher sugar content compared to those of rats fed a control diet. These results suggest that lignosulfonic acid suppresses the rise in blood glucose levels through inhibition of α-glucosidase activity and intestinal glucose absorption. Additionally, lignosulfonic acid suppressed increase of blood glucose level in diabetic KK-Ay mice. These results suggest that lignosulfonic acid may be useful as an anti-diabetes agent. | |||||||||||
言語 | en | |||||||||||
書誌情報 |
ja : 室蘭工業大学紀要 en : Memoirs of the Muroran Institute of Technology 巻 66, p. 11-15, 発行日 2017-03-24 |
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注記 | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | 特集 | |||||||||||
言語 | ja | |||||||||||
出版者 | ||||||||||||
言語 | ja | |||||||||||
出版者 | 室蘭工業大学 | |||||||||||
日本十進分類法 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 493.123 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | PISSN | |||||||||||
収録物識別子 | 13442708 | |||||||||||
書誌レコードID | ||||||||||||
収録物識別子タイプ | NCID | |||||||||||
収録物識別子 | AA11912609 | |||||||||||
権利 | ||||||||||||
言語 | ja | |||||||||||
権利情報 | © 2017 室蘭工業大学 | |||||||||||
著者版フラグ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
フォーマット | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | application/pdf |