@article{oai:muroran-it.repo.nii.ac.jp:00010468, author = {MATSUZAKI, Shinji and AZUMA, Kento and LIN, Xuguang and リン, シュウグアン and KURAGANO, Masahiro and 倉賀野, 正弘 and UWAI, Koji and 上井, 幸司 and 山中, 真也 and YAMANAKA, Shinya and TOKURAKU, Kiyotaka and 徳樂, 清孝}, issue = {1}, journal = {SCIENTIFIC REPORTS}, month = {}, note = {application/pdf, Livestock farming is affected by the occurrence of infectious diseases, but outbreaks can be prevented by proper sanitary control measures. Calcium hydroxide (Ca(OH)(2)), commonly called slaked lime, powder is traditionally used as a disinfectant to prevent infectious diseases in livestock. Since Ca(OH)(2) can inactivate a wide variety of pathogens, has a small environmental impact, does not require a disinfection tank (i.e., can be spread directly on the ground) and is produced inexpensively worldwide, it is used for the prevention of epidemics on farms worldwide. Water is essential for the strong alkalinity that underlies its disinfecting effect, but it is unknown how much water is required under field conditions. In addition, Ca(OH)(2) reacts with carbon dioxide in the environment, reducing its pH, but it is unclear how long its degradation takes under actual field use. Thus, we measured the water adsorption ability of Ca(OH)(2)-based disinfectants and its relation to disinfectant activity, as assessed by colony counts and live/dead staining and observation. We found that 15-20% (w/w) water in Ca(OH)(2) was necessary for disinfection to occur in practice. Moreover, we found that the pH of Ca(OH)(2) decreased within about two weeks to one month under actual use in practical conditions and lost its ability to disinfect. We further showed that granules prepared from Ca(OH)(2) and zeolite maintained high alkalinity more than twice as long as calcium powder. These findings will help to establish a suitable method of applying Ca(OH)(2) to protect farms from infectious diseases.}, title = {Farm use of calcium hydroxide as an effective barrier against pathogens}, volume = {11}, year = {2021}, yomi = {クラガノ, マサヒロ and ウワイ, コウジ and ヤマナカ, シンヤ and トクラク, キヨタカ} }