@article{oai:muroran-it.repo.nii.ac.jp:00008530, author = {三浦, 淳 and MIURA, Jun and 湯浅, 友典 and YUASA, Tomonori and 千葉, 武雄 and CHIBA, Takeo and 相津, 佳永 and AIZU, Yoshihisa and 佐々木, 春喜 and SASAKI, Haruki}, journal = {室蘭工業大学紀要, Memoirs of the Muroran Institute of Technology}, month = {Mar}, note = {application/pdf, Recently, we have developed a dawn simulation apparatus described elsewhere in this proceeding. This study aimed to evaluate its clinical efficacy. The study comprised the four-day baseline period (D1-D5), the four-day trial period (D5-D9), and the four-day follow-up period (D9-D13). During the whole period, the 24-hour activity was recorded. During the trial period, the gradually increasing light from 0 to 250 lux at eyelids was given between one and four o’clock, followed by collection of saliva to measure the melatonin concentration. The hourly activity between four and five increased significantly during the trial period, probably due to the activity to collect saliva. In addition, the hourly activity between five and six increased significantly on D9 compared to the baseline period, suggesting increased alertness. However, the activity after six did not change significantly. In conclusion, simulated dawn provided by our new apparatus may increase morning alertness for a limited time., 研究報告}, pages = {117--121}, title = {擬似夜明け療法による生体リズム位相調節の試み}, volume = {63}, year = {2014}, yomi = {ミウラ, ジュン and ユアサ, トモノリ and チバ, タケオ and アイズ, ヨシヒサ and ササキ, ハルキ} }