WEKO3
アイテム
{"_buckets": {"deposit": "06d365c8-92a5-43e2-b692-7a2e44cf382d"}, "_deposit": {"created_by": 18, "id": "10474", "owners": [18], "pid": {"revision_id": 0, "type": "depid", "value": "10474"}, "status": "published"}, "_oai": {"id": "oai:muroran-it.repo.nii.ac.jp:00010474", "sets": ["46", "242"]}, "author_link": ["10436", "58584"], "item_79_biblio_info_10": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "3316", "bibliographicPageStart": "3308", "bibliographicVolumeNumber": "8", "bibliographic_titles": [{"bibliographic_title": "FOOD SCIENCE \u0026 NUTRITION", "bibliographic_titleLang": "en"}]}]}, "item_79_description_23": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_79_description_7": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We had previously shown that the intake of scallop mantle tissue resulted in the death of mice and rats. In this study, we investigated the liver injury caused by mantle tissue to clarify the mechanism behind its toxicity. Mantle toxin increased lipid peroxidation and decreased the reductive thiol content as well as the DPPH radical scavenging activity, catalase activity, and glutathione content in the liver of the mice. These results suggested that the mantle tissue diet caused oxidative stress through the decrease in antioxidants. In addition, mantle toxin increased the mRNA expression of endoplasmic reticulum (ER) stress- and inflammation-induced genes and the protein expression of caspase-3 and Bax (which induce apoptosis), suggesting that the mantle tissue diet causes apoptosis through oxidative stress, ER stress, and inflammation in the liver tissue. Such liver injury may be an essential cause of the rodent demise.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_79_link_17": {"attribute_name": "出版者版へのリンク", "attribute_value_mlt": [{"subitem_link_text": "10.1002/fsn3.1608", "subitem_link_url": "https://doi.org/10.1002/fsn3.1608"}]}, "item_79_link_5": {"attribute_name": "室蘭工業大学研究者データベースへのリンク", "attribute_value_mlt": [{"subitem_link_text": "長谷川 靖(HASEGAWA Yasushi)", "subitem_link_url": "http://rdsoran.muroran-it.ac.jp/html/100000200_ja.html"}]}, "item_79_publisher_11": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "WILEY", "subitem_publisher_language": "en"}]}, "item_79_relation_18": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1002/fsn3.1608", "subitem_relation_type_select": "DOI"}}]}, "item_79_rights_19": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "https://creativecommons.org/licenses/by/4.0/", "subitem_rights_language": "en"}]}, "item_79_source_id_12": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2048-7177", "subitem_source_identifier_type": "EISSN"}]}, "item_79_subject_9": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "490", "subitem_subject_scheme": "NDC"}]}, "item_79_text_4": {"attribute_name": "著者ID(非表示)", "attribute_value_mlt": [{"subitem_text_value": "1000080261387"}]}, "item_79_version_type_21": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "KARIYA, Takahide", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "58584", "nameIdentifierScheme": "WEKO"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "10103", "affiliationNameIdentifierScheme": "kakenhi"}], "affiliationNames": [{"affiliationName": "室蘭工業大学", "affiliationNameLang": "ja"}, {"affiliationName": "Muroran Institute of Technology", "affiliationNameLang": "en"}]}], "creatorNames": [{"creatorName": "HASEGAWA, Yasushi", "creatorNameLang": "en"}, {"creatorName": "長谷川, 靖", "creatorNameLang": "ja"}, {"creatorName": "ハセガワ, ヤスシ", "creatorNameLang": "ja-Kana"}], "familyNames": [{"familyName": "HASEGAWA", "familyNameLang": "en"}, {"familyName": "長谷川", "familyNameLang": "ja"}, {"familyName": "ハセガワ", "familyNameLang": "ja-Kana"}], "givenNames": [{"givenName": " Yasushi", "givenNameLang": "en"}, {"givenName": "靖", "givenNameLang": "ja"}, {"givenName": "ヤスシ", "givenNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "10436", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000080261387", "nameIdentifierScheme": "NRID", "nameIdentifierURI": "https://nrid.nii.ac.jp/ja/nrid/1000080261387"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2021-06-29"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "FSN_2020_8_3308_3316.pdf", "filesize": [{"value": "1.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 1100000.0, "url": {"label": "FSN_2020_8_3308_3316", "objectType": "fulltext", "url": "https://muroran-it.repo.nii.ac.jp/record/10474/files/FSN_2020_8_3308_3316.pdf"}, "version_id": "1a39d2ac-9b35-45f3-a3d2-74b7f9da6655"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "food", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "liver", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "scallop mantle", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "toxin", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Scallop mantle toxin induces apoptosis in liver tissues of mice", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Scallop mantle toxin induces apoptosis in liver tissues of mice", "subitem_title_language": "en"}]}, "item_type_id": "79", "owner": "18", "path": ["46", "242"], "permalink_uri": "http://hdl.handle.net/10258/00010413", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-06-29"}, "publish_date": "2021-06-29", "publish_status": "0", "recid": "10474", "relation": {}, "relation_version_is_last": true, "title": ["Scallop mantle toxin induces apoptosis in liver tissues of mice"], "weko_shared_id": -1}
Scallop mantle toxin induces apoptosis in liver tissues of mice
http://hdl.handle.net/10258/00010413
http://hdl.handle.net/10258/00010413f70e5aec-3cec-4f12-a173-7cd578108b83
名前 / ファイル | ライセンス | アクション |
---|---|---|
FSN_2020_8_3308_3316 (1.1 MB)
|
|
Item type | 学術雑誌論文 / Journal Article.(1) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
公開日 | 2021-06-29 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | Scallop mantle toxin induces apoptosis in liver tissues of mice | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | food | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | liver | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | scallop mantle | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | toxin | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
アクセス権 | ||||||||||||
アクセス権 | open access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
著者 |
KARIYA, Takahide
× KARIYA, Takahide× 長谷川, 靖
WEKO
10436
|
|||||||||||
室蘭工業大学研究者データベースへのリンク | ||||||||||||
長谷川 靖(HASEGAWA Yasushi) | ||||||||||||
http://rdsoran.muroran-it.ac.jp/html/100000200_ja.html | ||||||||||||
抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | We had previously shown that the intake of scallop mantle tissue resulted in the death of mice and rats. In this study, we investigated the liver injury caused by mantle tissue to clarify the mechanism behind its toxicity. Mantle toxin increased lipid peroxidation and decreased the reductive thiol content as well as the DPPH radical scavenging activity, catalase activity, and glutathione content in the liver of the mice. These results suggested that the mantle tissue diet caused oxidative stress through the decrease in antioxidants. In addition, mantle toxin increased the mRNA expression of endoplasmic reticulum (ER) stress- and inflammation-induced genes and the protein expression of caspase-3 and Bax (which induce apoptosis), suggesting that the mantle tissue diet causes apoptosis through oxidative stress, ER stress, and inflammation in the liver tissue. Such liver injury may be an essential cause of the rodent demise. | |||||||||||
言語 | en | |||||||||||
書誌情報 |
en : FOOD SCIENCE & NUTRITION 巻 8, 号 7, p. 3308-3316, 発行日 2020 |
|||||||||||
出版者 | ||||||||||||
言語 | en | |||||||||||
出版者 | WILEY | |||||||||||
出版者版へのリンク | ||||||||||||
10.1002/fsn3.1608 | ||||||||||||
https://doi.org/10.1002/fsn3.1608 | ||||||||||||
DOI | ||||||||||||
関連タイプ | isIdenticalTo | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | 10.1002/fsn3.1608 | |||||||||||
日本十進分類法 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 490 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | EISSN | |||||||||||
収録物識別子 | 2048-7177 | |||||||||||
権利 | ||||||||||||
言語 | en | |||||||||||
権利情報 | https://creativecommons.org/licenses/by/4.0/ | |||||||||||
著者版フラグ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
フォーマット | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | application/pdf |